Optical coherence photoacoustic microscopy: accomplishing optical coherence tomography and photoacoustic microscopy with a single light source

Introduction: Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy

The editors introduce the Biomedical Optics Express feature issue, “Advances in Optical Coherence Tomography, Photoacoustic Imaging, and Microscopy,” which combines three technical areas from the 2010 Optical Society of America (OSA), Biomedical Optics (BIOMED) Topical Meeting held on 11–14 April in Miami, Florida, and includes contributions from conference attendees. © 2010 Optical Society of ...

Simultaneous optical coherence tomography and autofluorescence microscopy with a single light source.

We have accomplished simultaneous spectral domain optical coherence tomography (SD-OCT) and autofluorescence (AF) microscopy with a broadband light source centered at 415 nm. The light source was provided by frequency-doubling of an ultra-fast broadband Ti:Sapphire laser. With a bandwidth of 8 nm, the visible SD-OCT achieved a depth resolution of ~12  μm. Since the two imaging modalities are pr...

All-optical photoacoustic microscopy

Three-dimensional photoacoustic microscopy (PAM) has gained considerable attention within the biomedical imaging community during the past decade. Detecting laser-induced photoacoustic waves by optical sensing techniques facilitates the idea of all-optical PAM (AOPAM), which is of particular interest as it provides unique advantages for achieving high spatial resolution using miniaturized embod...

Optical-Resolution Photoacoustic Microscopy

Pure optical photoacoustic microscopy

The concept of pure optical photoacoustic microscopy(POPAM) was proposed based on optical rastering of a focused excitation beam and optically sensing the photoacoustic signal using a microring resonator fabricated by a nanoimprinting technique. After the refinements of the microring's working wavelength and in the resonator structure and mold fabrication, an ultrahigh Q factor of 3.0×10(5) was...